Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation
Status: Recruiting
Location: See location...
Intervention Type: Device, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
A randomised controlled clinical trial to assess efficacy of convergent ablation with the LARIAT procedure, as compared to standard endocardial catheter ablation in patients with long-standing persistent atrial fibrillation (AF).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:
• Age \> 18 years; \< 80 years
• Persistent AF \> 1-year duration
• Left atrium size \< 6cm
• Pts should be able to provide written informed consent.
Locations
Other Locations
United Kingdom
St Bartholomew's Hospital
RECRUITING
London
Contact Information
Primary
Syed Ahsan
syedahsan@nhs.net
020 7377 7000
Backup
Shahana Hussain
shahana.hussain2@nhs.net
020 7377 7000
Time Frame
Start Date: 2024-08-02
Estimated Completion Date: 2026-10
Participants
Target number of participants: 48
Treatments
Experimental: Convergent AF Ablation with Left Atrial Appendage Exclusion
Two Staged Convergent AF Ablation Procedure~Stage 1 - Minimally Invasive Surgical Epicardial Ablation Procedure with concomitant LAA exclusion (LARIAT procedure)~Stage 2 - Percutaneous Endocardial Catheter Ablation
Active_comparator: Standard Endocardial Catheter Ablation
Standard Endocardial Catheter Ablation
Related Therapeutic Areas
Sponsors
Collaborators: AtriCure, Inc.
Leads: Barts & The London NHS Trust